Bupropion is a prescription only oral medicine used to support smoking cessation. Originally developed as an antidepressant, it acts on brain chemicals involved in nicotine craving and withdrawal, and does not contain nicotine itself.
In Australia, bupropion is PBS listed for eligible quit attempts, usually taken as a course starting one to two weeks before the quit date. A doctor screens for seizure history and other medicines before prescribing, and combines it with a structured quit plan for the best chance of success.